Bioactive parathyroid hormone in the rat: effects of calcium and calcitriol.

@article{Seshadri1985BioactivePH,
  title={Bioactive parathyroid hormone in the rat: effects of calcium and calcitriol.},
  author={Mandalam Subramaniam Seshadri and Tim Frankel and Dianne Lissner and R S Mason and Solomon Posen},
  journal={Endocrinology},
  year={1985},
  volume={117 6},
  pages={2417-23}
}
Bioactive PTH was measured in Wistar rats under a variety of experimental conditions. The mean activity in normal rat sera was 0.17 +/- 0.12 ng/ml (expressed in terms of bovine PTH 1-34). Sera from animals reared on a vitamin D deficient diet showed a mean value of 0.46 +/- 0.24 ng/ml (P less than 0.01), whereas sera from animals with 1,25-dihydroxyvitamin D (1,25(OH)2D) deficiency had a mean activity of 0.62 +/- 0.23 ng/ml (P less than 0.01). Dietary calcium deficiency also resulted in high… CONTINUE READING