Bioactive metabolites from the Caribbean sponge Aka coralliphagum.

  title={Bioactive metabolites from the Caribbean sponge Aka coralliphagum.},
  author={A. Grube and M. Assmann and E. Lichte and F. Sasse and J. Pawlik and M. K{\"o}ck},
  journal={Journal of natural products},
  volume={70 4},
The chemistry of the burrowing sponge Aka coralliphagum was investigated to identify chemically labile secondary metabolites. The HPLC-MS analysis of the two growth forms typica and incrustans revealed different metabolites. The previously unknown sulfated compounds siphonodictyals B1 to B3 (6-8), corallidictyals C (9) and D (10), and siphonodictyal G (11) were isolated, and their structures were elucidated by NMR and MS experiments. The compounds were tested in a DPPH assay, in antimicrobial… Expand
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