Bioactive constituents from gum guggul (Commiphora wightii).

  title={Bioactive constituents from gum guggul (Commiphora wightii).},
  author={Nanqun Zhu and Mohamed M. Rafi and Robert S. DiPaola and Ji Xin and Chee Kok Chin and Vladimir Badmaev and Geetha Ghai and Robert T. Rosen and Chi-Tang Ho},
  volume={56 7},
Bioactivity-directed fractionation and purification afforded cytotoxic components of Commiphora wightii. The exudates of C. wightii were extracted with EtOAc and the extract was subjected to repeated column chromatography. A fraction showing cytotoxic activity was characterized as a mixture of two ferulates with an unusual skeleton by spectral and chemical methods, including by NMR, GC-MS and chemical derivatization. This fraction also showed moderate scavenging effect against 2,2-diphenyl-1… CONTINUE READING

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