Bioactive compounds of Shuang-Huang-Lian prescription and an insight into its binding mechanism by β2 -adrenoceptor chromatography coupled with site-directed molecular docking.

@article{Wang2017BioactiveCO,
  title={Bioactive compounds of Shuang-Huang-Lian prescription and an insight into its binding mechanism by β2 -adrenoceptor chromatography coupled with site-directed molecular docking.},
  author={Jing Wang and Fengwu Li and Kaizhu Zeng and Qian Li and Xinfeng Zhao and Xiaohui Zheng},
  journal={Journal of separation science},
  year={2017},
  volume={40 22},
  pages={
          4357-4365
        }
}
Owing to the promising clinical efficacy and relatively simple composition, Shuang-Huang-Lian prescription is widely prescribed for the treatment of acute upper respiratory tract infection and acute bronchitis in practice. This necessitates the understanding of the bioactive compounds of the prescription and their binding mechanism to β2 -adrenoceptor, which mediates the aforementioned ailments. In this work, a column containing immobilized β2 -adrenoceptor was prepared using a diazonium salt… CONTINUE READING
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