Bioactive cembrane diterpenoids of Anisomeles indica.

@article{Chen2008BioactiveCD,
  title={Bioactive cembrane diterpenoids of Anisomeles indica.},
  author={Yu-Li Chen and Yu Hong Lan and Pei-Wen Hsieh and Chin-Chung Wu and Shu-li Chen and C H Yen and F. -H. Chang and W R Hung and Yang-Chang Wu},
  journal={Journal of natural products},
  year={2008},
  volume={71 7},
  pages={1207-12}
}
Five new cembrane-type diterpenoids with a trans-fused alpha-methylene-gamma-lactone (1-5), a new flavonoid glucoside (6), and 17 known compounds were isolated from a methanol extract of Anisomeles indica. The structures of 1-6 were elucidated by spectroscopic analysis, and the absolute configuration of compound 1 was determined using the modified Mosher's method. Compound 8 (4,5-epoxovatodiolide) exhibited cytotoxicity against a small panel of human cancer cell lines. Additionally, compounds 4… CONTINUE READING

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