Bioactive Nortriterpenoids from Schisandra grandiflora.

  title={Bioactive Nortriterpenoids from Schisandra grandiflora.},
  author={Wei-Lie Xiao and Yan-Qing Gong and R Wang and Zhi-Ying Weng and Xiao Luo and Xiao-nian Li and Guang-Yu Yang and Fei He and Jianxin Pu and Liu-meng Yang and Yong-Tang Zheng and Yang Lu and Han-Dong Sun},
  journal={Journal of natural products},
  volume={72 9},
Three new nortriterpenoids, schigrandilactones A-C (1-3), along with eight known compounds, were isolated from an organic solvent extract of Schisandra grandiflora. Compounds 1 and 2 feature a spirocyclic moiety in their structures, and compound 3 was characterized with a new oxygenated pattern. The relative configurations of 1 and 3 were determined through single-crystal X-ray experiments. In addition, compounds 1 and 2 displayed cytotoxic activity against two human cancer cell lines, and… CONTINUE READING