Bioactive Metabolites from Spilanthes acmella Murr.

@article{Prachayasittikul2009BioactiveMF,
  title={Bioactive Metabolites from Spilanthes acmella Murr.},
  author={Supaluk Prachayasittikul and Saowapa Suphapong and Apilak Worachartcheewan and Ratana Lawung and Somsak Ruchirawat and Virapong Prachayasittikul},
  journal={Molecules},
  year={2009},
  volume={14},
  pages={850 - 867}
}
Spilanthes acmella Murr. (Compositae) has been used as a traditional medicine for toothache, rheumatism and fever. Its extracts had been shown to exhibit vasorelaxant and antioxidant activities. Herein, its antimicrobial, antioxidant and cytotoxic activities were evaluated. Agar dilution method assays against 27 strains of microorganisms were performed. Results showed that fractions from the chloroform and methanol extracts inhibited the growth of many tested organisms, e.g. Corynebacterium… 
STUDIES ON ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF SPILANTHES ACMELLA L
For a long period of time, nature has been a great source of medicinal agents. In present study, antibacterial and antioxidant activity of different extracts of Spilanthes acmella L. were evaluated
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Extracts of dedifferentiated cultures of Spilanthes acmella Murr. possess antioxidant and anthelmintic properties and hold promise as an alternative source of herbal medicine
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The results of this study verify the potential of Spilanthes as a reservoir of bioactive agents and also substantiate the value of callus cultures as a new source of anthelmintic and antioxidant compounds.
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Effect of Spilanthes acmella hydroethanolic extract activity on tumour cell actin cytoskeleton
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The cytotoxicity of a hydroethanolic extract of the inflorescence of S. acmella is verified and its effects on the cytoskeleton of tumour cells are examined, confirming the data obtained from the MTT assay that gave high cytot toxicity.
Anti-trypanosomal Phenolic Derivatives from Baccharis uncinella
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Bioassay-guided fractionation of the EtOH extract of the aerial parts of Baccharis uncinella C. DC led to identification of two cinnamic acid derivatives, two flavones, and three chlorogenic acids, which displayed in vitro anti-trypanosomal activity.
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