Bioactive 7-Oxabicyclic[6.3.0]lactam and 12-Membered Macrolides from a Gorgonian-Derived Cladosporium sp. Fungus

@article{Cao2015Bioactive7A,
  title={Bioactive 7-Oxabicyclic[6.3.0]lactam and 12-Membered Macrolides from a Gorgonian-Derived Cladosporium sp. Fungus},
  author={Fei Cao and Q. Yang and C. Shao and C. Kong and Juan-Juan Zheng and Yun-feng Liu and Chang-yun Wang},
  journal={Marine Drugs},
  year={2015},
  volume={13},
  pages={4171 - 4178}
}
One new bicyclic lactam, cladosporilactam A (1), and six known 12-membered macrolides (2–7) were isolated from a gorgonian-derived Cladosporium sp. fungus collected from the South China Sea. Their complete structural assignments were elucidated by comprehensive spectroscopic investigation. Quantum chemistry calculations were used in support of the structural determination of 1. The absolute configuration of 1 was determined by calculation of its optical rotation. Cladosporilactam A (1) was the… Expand
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