BioSig: An Imaging Bioinformatic System for Studying Phenomic

  title={BioSig: An Imaging Bioinformatic System for Studying Phenomic},
  author={Bahram Parvin and Qing Yang and Gerald Fontenay and Mary Helen Barcellos-Hoff},
  journal={IEEE Computer},
F unctional genomics—understanding how a genome is expressed to produce myriad cell phenotypes—presents the core challenge of the postgenomic era. Using genomic information to understand the biology of complex organisms requires comprehensive knowledge of the dynamics of phenotype generation and maintenance. A phenotype results from selective expression of the genome, creating a history of the cell and its response to the extracellular environment. Defining cell phenomes requires tracking the… CONTINUE READING