Bio-Revitalization: Effects of NASHA on Genes Involving Tissue Remodeling

@article{Avantaggiato2015BioRevitalizationEO,
  title={Bio-Revitalization: Effects of NASHA on Genes Involving Tissue Remodeling},
  author={Anna Avantaggiato and Ambra Girardi and Annalisa Palmieri and Michele Pascali and Francesco Carinci},
  journal={Aesthetic Plastic Surgery},
  year={2015},
  volume={39},
  pages={459-464}
}
BackgroundThe “non-animal stabilized hyaluronic acid” (NASHA) is a widely used product in bio-revitalization injective procedures in esthetic medicine. The present research aimed to quantitatively evaluate the therapeutic effect of one of the more used bio-revitalization products on cultured dermal fibroblasts. RT-PCR was used for gene expression profiling of some proteins known to be relevant in skin homeostasis.MethodsHuman dermal fibroblasts were seeded on a culture medium enriched with a… Expand
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Hyaluronic acid: A review on its biology, aspects of drug delivery, route of administrations and a special emphasis on its approved marketed products and recent clinical studies.
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The mechanistic behavior of HA pertaining to its biological synthesis and degradation and the administration of some noteworthy and recent HA based formulations through different routes for application in various physiological conditions are discussed. Expand
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