Binge-eating disorder: Clinical and therapeutic advances.

  title={Binge-eating disorder: Clinical and therapeutic advances.},
  author={Peter H. Hutson and Iris Monique Balodis and Marc N. Potenza},
  journal={Pharmacology & therapeutics},
Binge-eating disorder (BED) is the most prevalent eating disorder with estimates of 2-5% of the general adult population. Nonetheless, its pathophysiology is poorly understood. Furthermore, there exist few therapeutic options for its effective treatment. Here we review the current state of binge-eating neurobiology and pharmacology, drawing from clinical therapeutic, neuroimaging, cognitive, human genetic and animal model studies. These studies, which are still in their infancy, indicate that… CONTINUE READING