Binding to chaperones allows import of a purified mitochondrial precursor into mitochondria.

Abstract

Refolding of the acid-unfolded precursor to mitochondrial aspartate aminotransferase (pmAAT) is inhibited when cytosolic Hsc70 is included in the refolding reaction (Artigues, A., Iriarte, A., and Martinez-Carrion, M. (1997) J. Biol. Chem. 272, 16852-16861). At low molar excess of Hsc70 pmAAT is recovered in insoluble aggregates containing equal amounts of… (More)

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Cite this paper

@article{Artigues2002BindingTC, title={Binding to chaperones allows import of a purified mitochondrial precursor into mitochondria.}, author={Antonio Artigues and Ana Iriarte and Marino Martinez-Carri{\'o}n}, journal={The Journal of biological chemistry}, year={2002}, volume={277 28}, pages={25047-55} }