Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic.

@article{Huang1995BindingSF,
  title={Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic.},
  author={Jiaxing Huang and T Dubnicoff and G J Liaw and Yongli Bai and Scott A. Valentine and J M Shirokawa and Judith A. Lengyel and Albert J. Courey},
  journal={Genes & development},
  year={1995},
  volume={9 24},
  pages={3177-89}
}
The Dorsal morphogen is a transcription factor that activates some genes and represses others to establish multiple domains of gene expression along the dorsal/ventral axis of the early Drosophila embryo. Repression by Dorsal appears to require accessory proteins that bind to corepression elements in Dorsal-dependent regulatory modules called ventral repression regions (VRRs). We have identified a corepression element in decapentaplegic (dpp), a zygotically active gene that is repressed by the… CONTINUE READING

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