Binding of the type 3 fimbriae of Klebsiella pneumoniae to human endothelial and urinary bladder cells.

@article{Tarkkanen1997BindingOT,
  title={Binding of the type 3 fimbriae of Klebsiella pneumoniae to human endothelial and urinary bladder cells.},
  author={A M Tarkkanen and Ritva Virkola and Steven Clegg and Timo K. Korhonen},
  journal={Infection and immunity},
  year={1997},
  volume={65 4},
  pages={
          1546-9
        }
}
Binding of the two identified type 3 fimbrial variants of Klebsiella pneumoniae to human endothelial EA-hy926 and bladder T24 cells was assessed. The recombinant Escherichia coli strain LE392(pFK12), expressing plasmid-encoded type 3 fimbriae of K. pneumoniae, adhered to both cell lines, and the fimbriae purified from the strain bound to both cell lines in a dose-dependent manner. Adhesiveness to both cell lines of chromosomally encoded type 3 fimbriae from K. pneumoniae IApc35 was lower. No… CONTINUE READING

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