Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides.

@article{Iwaarden1994BindingOS,
  title={Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides.},
  author={J Freek van Iwaarden and J C Pikaar and Janet Storm and Ellen Brouwer and J. C. Barendrecht Verhoef and Ronald S. Oosting and Lambert M G van Golde and Jos A. G. van Strijp},
  journal={The Biochemical journal},
  year={1994},
  volume={303 ( Pt 2)},
  pages={407-11}
}
Surfactant protein A (SP-A) enhances the phagocytosis of opsonized and non-opsonized bacteria by alveolar macrophages, but it is not known with which component of the bacterial surface it associates. We investigated the interaction of SP-A with lipopolysaccharides (LPS), which are important biologically active constituents of the outer membranes of Gram-negative bacteria. Flow cytometry was used to study the binding of fluorescein isothiocyanate-labelled SP-A either to LPS of various chain… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 63 extracted citations

Similar Papers

Loading similar papers…