Binding of substance P to monolayers and vesicles made of phosphatidylcholine and/or phosphatidylserine.

@article{Duplaa1992BindingOS,
  title={Binding of substance P to monolayers and vesicles made of phosphatidylcholine and/or phosphatidylserine.},
  author={H Duplaa and Odile Convert and Anne Marie Sautereau and J. F. Tocanne and G{\'e}rard Chassaing},
  journal={Biochimica et biophysica acta},
  year={1992},
  volume={1107 1},
  pages={12-22}
}
Analyses of interactions between substance P (SP) and phospholipids were performed by combined surface pressure and surface potential measurements in monolayers and by 13C-NMR experiments on liposomes. This study was carried out using synthetic SP molecules: [1-13C-Gly9]SP and [1-13C-Gly2]SP. Injection of SP into the aqueous subphase led to an expansion of phosphatidylcholine (PtdCho) or phosphatidylserine (PtdSer) monolayer surface area. An apparent association constant of SP for PtdSer was… CONTINUE READING