Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase.

Abstract

Tissue factor (TF) is the cellular receptor for an activated form of clotting factor VII (VIIa) and the binding of factor VII(a) to TF initiates the coagulation cascade. Sequence and structural patterns extracted from a global alignment of TF confers homology with interferon receptors of the cytokine receptor super family. Several recent studies suggested… (More)

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@article{Pendurthi1997BindingOF, title={Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase.}, author={Usha R. Pendurthi and Deoraj Alok and Lan Rao}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1997}, volume={94 23}, pages={12598-603} }