Binding of albumin promotes bacterial survival at the epithelial surface.

  title={Binding of albumin promotes bacterial survival at the epithelial surface.},
  author={Arne Egesten and Inga-Maria Frick and Matthias M{\"o}rgelin and Anders I. Olin and Lars Bj{\"o}rck},
  journal={The Journal of biological chemistry},
  volume={286 4},
Human serum albumin (HSA) is the dominating protein in human plasma. Many bacterial species, especially streptococci, express surface proteins that bind HSA with high specificity and affinity, but the biological consequences of these protein-protein interactions are poorly understood. Group G streptococci (GGS), carrying the HSA-binding protein G, colonize the skin and the mucosa of the upper respiratory tract, mostly without causing disease. In the case of bacterial invasion, pro-inflammatory… CONTINUE READING
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Bacterial immunoglobulin-binding proteins

  • M.P.D. Boyle
  • 1990

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