Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation

@article{Sewack2001BindingOT,
  title={Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation},
  author={Gerald F. Sewack and Thomas W. Ellis and Ulla Hansen},
  journal={Molecular and Cellular Biology},
  year={2001},
  volume={21},
  pages={1404 - 1415}
}
ABSTRACT The TATA sequence of the human, estrogen-responsive pS2 promoter is complexed in vivo with a rotationally and translationally positioned nucleosome (NUC T). Using a chromatin immunoprecipitation assay, we demonstrate that TATA binding protein (TBP) does not detectably interact with this genomic binding site in MCF-7 cells in the absence of transcriptional stimuli. Estrogen stimulation of these cells results in hyperacetylation of both histones H3 and H4 within the pS2 chromatin… 

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An Array of Positioned Nucleosomes Potentiates Thyroid Hormone Receptor Action in Vivo *

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Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex*

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