Binding of Hydrogen Sulfide by Bismuth Does Not Prevent Dextran Sulfate-Induced Colitis in Rats

@article{Furne2004BindingOH,
  title={Binding of Hydrogen Sulfide by Bismuth Does Not Prevent Dextran Sulfate-Induced Colitis in Rats},
  author={Julie K. Furne and Fabrizis L. Suarez and Stephen L. Ewing and John R. Springfield and Michael D. Levitt},
  journal={Digestive Diseases and Sciences},
  year={2004},
  volume={45},
  pages={1439-1443}
}
Several lines of evidence suggest that ulcerative colitis could be caused by excessive bacterial production of H2S in the colon. A rodent model of colitis involves the feeding of nonabsorbable, carbohydrate-bound sulfate in the form of dextran sulfate or carrageenan. The observation that metronidazole blocks the development of this colitis suggested that the injurious agent could be a sulfur-containing compound (such as H2S) that is released during the bacterial metabolism of the nonabsorbed… Expand
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Dear Sir: We read with interest the recent article by Wallace et al1 that indicates both endogenous and exogenous hydrogen sulphide (H2S) promote resolution of experimental colitis. Inhibition of H2SExpand
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