Binding of HIV-1 Vpr protein to the human homolog of the yeast DNA repair protein RAD23 (hHR23A) requires its xeroderma pigmentosum complementation group C binding (XPCB) domain as well as the ubiquitin-associated 2 (UBA2) domain.

Abstract

The human homolog of the yeast DNA repair protein RAD23, hHR23A, has been found previously to interact with the human immunodeficiency virus, type 1 accessory protein Vpr. hHR23A is a modular protein containing an N-terminal ubiquitin-like (UBL) domain and two ubiquitin-associated domains (UBA1 and UBA2) separated by a xeroderma pigmentosum complementation… (More)
DOI: 10.1074/jbc.M113.534453

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@article{Jung2014BindingOH, title={Binding of HIV-1 Vpr protein to the human homolog of the yeast DNA repair protein RAD23 (hHR23A) requires its xeroderma pigmentosum complementation group C binding (XPCB) domain as well as the ubiquitin-associated 2 (UBA2) domain.}, author={Jinwon Jung and In-Ja L. Byeon and Maria DeLucia and Leonardus M.I. Koharudin and Jinwoo Ahn and Angela M. Gronenborn}, journal={The Journal of biological chemistry}, year={2014}, volume={289 5}, pages={2577-88} }