Binding assistance triggering attachments of hairpin DNA onto gold nanoparticles.

Abstract

Here, we present a strategy to trigger monovalent attachments of thoilated hairpin DNA onto AuNP, assisted by molecular binding. Without binding helper strands, it is hard to control the attachments of thiolated hairpin DNA, because of spatial hindrances. By introducing a binding helper strand, the thiol-group can be brought into close proximity to the… (More)
DOI: 10.1021/ac402908y

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