Binding and signalling properties of a growth hormone enhancing monoclonal antibody


We have used a sequential, qualitative biosensor based assay to demonstrate that OA15, a monoclonal antibody which enhances in vivo the activity of bovine growth hormone (bGH) does not disrupt the interaction between bGH and its cognate receptor (as represented by recombinant bovine GH binding protein -rbGHBP). We have confirmed this using a classical cell… (More)
DOI: 10.1023/A:1006989232646


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