Binding and internalization of gold-labeled IFN-gamma by human Raji cells.

@article{Filgueira1989BindingAI,
  title={Binding and internalization of gold-labeled IFN-gamma by human Raji cells.},
  author={Luis Filgueira and Peter Groscurth and Michel Aguet},
  journal={Journal of immunology},
  year={1989},
  volume={142 10},
  pages={3436-9}
}
Binding and internalization of gold-labeled IFN-gamma (IFN-gamma/Au) by human Raji cells was examined by scanning and transmission electron microscopy. For SEM, visualization of gold particles was enhanced by the silver enhancement technique and by backscattered electron imaging. Binding studies revealed distinct labeling of microvilli-bearing cells after incubation with at least 10 U/ml IFN-gamma/Au, whereas cells with a smooth surface showed substantially lower labeling. After application of… CONTINUE READING
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