Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors.

@article{Weng1998BindingAF,
  title={Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors.},
  author={Y Weng and Salvatore J. Siciliano and K E Waldburger and Anna Sirotina-Meisher and Mary Jo Staruch and Bruce L. Daugherty and Sandra L Gould and Martin S. Springer and Julie A Demartino},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 29},
  pages={18288-91}
}
IP10 and MIG are two members of the CXC branch of the chemokine superfamily whose expression is dramatically up-regulated by interferon (IFN)-gamma. The proteins act largely on natural killer (NK)-cells and activated T-cells and have been implicated in mediating some of the effects of IFN-gamma and lipopolysaccharides (LPSs), as well as T-cell-dependent anti-tumor responses. Recently both chemokines have been shown to be functional agonists of the same G-protein-coupled receptor, CXCR3. We now… CONTINUE READING
78 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 78 extracted citations

Similar Papers

Loading similar papers…