Binding and effect of atrial natriuretic factor on cyclic GMP formation and alpha-MSH secretion of intermediate pituitary cells.

Abstract

The present study shows for the first time that in proopiomelanocortin cells of the rat intermediate pituitary gland ANF binds to two receptor forms, with apparent molecular weights of 150K and 70K. Scatchard plots revealed specific and high affinity non-interacting sites, with a KD value of about 3 nM and a density of 7,000 sites/cell. The presence of… (More)

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Cite this paper

@article{LutzBucher1988BindingAE, title={Binding and effect of atrial natriuretic factor on cyclic GMP formation and alpha-MSH secretion of intermediate pituitary cells.}, author={Bernadette Lutz-Bucher and T Boudjada and Stela Heisler and G. Pelletier and Bettina Koch}, journal={Biochemical and biophysical research communications}, year={1988}, volume={155 1}, pages={83-90} }