Binding and Clearance of Radioactive Adrenaline and Noradrenaline in Sheep Blood

  title={Binding and Clearance of Radioactive Adrenaline and Noradrenaline in Sheep Blood},
  author={S. El-Bahr and H. Kahlbacher and M. Patzl and R. Palme},
  journal={Veterinary Research Communications},
An understanding of the conditions influencing protein binding of catecholamines (CAs) is important in studying their metabolic effects. Unfortunately, reports on plasma protein binding of CAs are scarce, conflicting and mainly performed in vitro.The aim of our in vivo and in vitro studies was to investigate binding and clearance of radioactive adrenaline (epinephrine) (3H-A), noradrenaline (norepinephrine) (3H-NA) and their metabolites in sheep blood. The time course of the radioactivity in… Expand
8 Citations
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