Binding analysis of ytterbium(III) complex containing 1,10-phenanthroline with DNA and its antimicrobial activity.

@article{Moodi2013BindingAO,
  title={Binding analysis of ytterbium(III) complex containing 1,10-phenanthroline with DNA and its antimicrobial activity.},
  author={Asieh Moodi and Mozhgan Khorasani-Motlagh and Meissam Noroozifar and Sona Niroomand},
  journal={Journal of biomolecular structure & dynamics},
  year={2013},
  volume={31 8},
  pages={
          937-50
        }
}
To evaluate the biological preference of [Yb(phen)₂(OH₂)Cl₃](H₂O)₂ (phen is 1,10-phenanthroline) for DNA, interaction of Yb(III) complex with DNA in Tris-HCl buffer is studied by various biophysical and spectroscopic techniques which reveal that the complex binds to DNA. The results of fluorescence titration reveal that [Yb(phen)₂(OH₂)Cl₃](H₂O)₂ has strongly quenched in the presence of DNA. The binding site number n, apparent binding constant K b, and the Stern-Volmer quenching constant K SV… CONTINUE READING
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