Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.

@article{Uchida2007BindingAB,
  title={Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.},
  author={Shinya Uchida and Souhei Kurosawa and Tomomi Fujino Oki and Yoshihisa Kato and Masato Nanri and Kenichiro Yoshida and Shizuo Yamada},
  journal={Life sciences},
  year={2007},
  volume={80 26},
  pages={2454-60}
}
The present study was undertaken to characterize the binding activities of propiverine and its N-oxide metabolites (1-methyl-4-piperidyl diphenylpropoxyacetate N-oxide: P-4(N-->O), 1-methyl-4-piperidyl benzilate N-oxide: DPr-P-4(N-->O)) toward L-type calcium channel antagonist receptors in the rat bladder and brain. Propiverine and P-4(N-->O) inhibited… CONTINUE READING