Binding Site Identification and Flexible Docking of Single Stranded RNA to Proteins Using a Fragment-Based Approach

@inproceedings{Beauchene2016BindingSI,
  title={Binding Site Identification and Flexible Docking of Single Stranded RNA to Proteins Using a Fragment-Based Approach},
  author={Isaure Chauvot de Beauchene and Sjoerd J. de Vries and Martin Zacharias},
  booktitle={PLoS Computational Biology},
  year={2016}
}
Protein-RNA docking is hampered by the high flexibility of RNA, and particularly single-stranded RNA (ssRNA). Yet, ssRNA regions typically carry the specificity of protein recognition. The lack of methodology for modeling such regions limits the accuracy of current protein-RNA docking methods. We developed a fragment-based approach to model protein-bound… CONTINUE READING