Binding Site Alteration Is Responsible for Field-Isolated Resistance to Bacillus thuringiensis Cry2A Insecticidal Proteins in Two Helicoverpa Species

@inproceedings{Caccia2010BindingSA,
  title={Binding Site Alteration Is Responsible for Field-Isolated Resistance to Bacillus thuringiensis Cry2A Insecticidal Proteins in Two Helicoverpa Species},
  author={Silvia Caccia and Carmen Sara Hern{\'a}ndez-Rodr{\'i}guez and Rod J. Mahon and Sharon Downes and William James and Nadine Bautsoens and Jeroen Van Rie and Juan Ferr{\'e}},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Evolution of resistance by target pests is the main threat to the long-term efficacy of crops expressing Bacillus thuringiensis (Bt) insecticidal proteins. Cry2 proteins play a pivotal role in current Bt spray formulations and transgenic crops and they complement Cry1A proteins because of their different mode of action. Their presence is critical in the control of those lepidopteran species, such as Helicoverpa spp., which are not highly susceptible to Cry1A proteins. In Australia, a… CONTINUE READING
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