Binding , Internalization , and Intracellular Processing of Proteins Interacting with Recycling Receptors

@inproceedings{BajzerSQ2001BindingI,
  title={Binding , Internalization , and Intracellular Processing of Proteins Interacting with Recycling Receptors},
  author={Zeljko BajzerSQ and Andrew and MyersSll and Stanimir Vuk-Pavlovii},
  year={2001}
}
  • Zeljko BajzerSQ, Andrew, +1 author Stanimir Vuk-Pavlovii
  • Published 2001
We measured time-dependent concentration changes of human interferon-ana (IFN) and human tumor necrosis factor-a (TNF) bound at the plasma membrane and internalized by human lung alveolar carcinoma A649 cells in the presence of excess free ligand. Concentration changes for these two ligands were substantially different. We modified our compartmental kinetic model encompassing receptor synthesis and receptor loss (Myers, A. C., Kovach, J. S . , and VukPavlovic, S . (1987) J. Biol. Chem. 262… CONTINUE READING