Binding, endocytosis, and degradation of model immune complexes by murine macrophages at various levels of activation.

Abstract

To determine if stimulation of macrophages enhances their capacity to recognize and process immune complexes, the binding, endocytosis, and degradation of soluble model immune complexes in murine macrophages have been measured. These complexes are composed of covalently crosslinked dimers and heavy oligomers of murine IgG antidinitrophenyl antibodies… (More)

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