Binding, coupling, and mRNA subtype heterogeneity of alpha 1-adrenergic receptors in cultured human RPE.

@article{MoroiFetters1995BindingCA,
  title={Binding, coupling, and mRNA subtype heterogeneity of alpha 1-adrenergic receptors in cultured human RPE.},
  author={S. E. Moroi-Fetters and O. Earley and A. Hirakata and M. Caron and G. Jaffe},
  journal={Experimental eye research},
  year={1995},
  volume={60 5},
  pages={
          527-32
        }
}
  • S. E. Moroi-Fetters, O. Earley, +2 authors G. Jaffe
  • Published 1995
  • Biology, Medicine
  • Experimental eye research
  • In retinal pigment epithelium, apically applied epinephrine changes the conductance of specific ions which subsequently affects the membrane voltage and stimulates transepithelial fluid transport. In this investigation, myo-[3H]inositol radiotracer studies, radioligand binding with [125I]HEAT, and ribonuclease protection assays were performed to examine the coupling of this receptor to phosphoinositide hydrolysis and the specific mRNA subtypes expressed in cultured human retinal pigment… CONTINUE READING
    10 Citations
    Adrenergic receptor activated ion transport in human fetal retinal pigment epithelium.
    • 60
    • PDF
    Epinephrine-induced increases in [Ca2+](in) and KCl-coupled fluid absorption in bovine RPE.
    • 35
    • PDF
    Distribution of alpha‐1 adrenoceptor subtypes in RNA and protein in rabbit eyes
    • 56
    Characterization of alpha(1)-adrenoceptor subtypes in the eye.
    • 52
    Ion channels in the RPE
    • 148
    • PDF

    References

    SHOWING 1-10 OF 30 REFERENCES
    Alpha-1-adrenergic modulation of K and Cl transport in bovine retinal pigment epithelium
    • 65
    • PDF
    Identification of alpha 1C-adrenergic receptor mRNA in bovine retinal pigment epithelium.
    • 20
    Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells.
    • 238
    Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine.
    • 272