Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator.

Abstract

Clostridium difficile binary toxin (CDT) is an actin-specific ADP-ribosyltransferase that is produced by various C. difficile isolates, including the "hypervirulent" NAP1/027 epidemic strains. In contrast to the two major toxins from C. difficile, toxin A and toxin B, little is known about the role of CDT in virulence or how C. difficile regulates its… (More)

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Cite this paper

@article{Carter2007BinaryTP, title={Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator.}, author={Glen P. Carter and Dena Lyras and David L. Allen and Kate E. Mackin and Pauline M. Howarth and Jennifer R O'Connor and Julian I. Rood}, journal={Journal of bacteriology}, year={2007}, volume={189 20}, pages={7290-301} }