Bimodal action of the flavonoid quercetin on basophil function: an investigation of the putative biochemical targets

@inproceedings{Chirumbolo2010BimodalAO,
  title={Bimodal action of the flavonoid quercetin on basophil function: an investigation of the putative biochemical targets},
  author={Salvatore Chirumbolo and Marta Marzotto and Anita Conforti and Antonio Vella and Riccardo Ortolani and Paolo Bellavite},
  booktitle={Clinical and molecular allergy : CMA},
  year={2010}
}
BACKGROUND Flavonoids, a large group of polyphenolic metabolites derived from plants have received a great deal of attention over the last several decades for their properties in inflammation and allergy. Quercetin, the most abundant of plant flavonoids, exerts a modulatory action at nanomolar concentrations on human basophils. As this mechanism needs to be elucidated, in this study we focused the possible signal transduction pathways which may be affected by this compound. METHODS K2-EDTA… CONTINUE READING
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