Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats.

@article{Goldie2013BilobalideAU,
  title={Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats.},
  author={Michelle Goldie and Sharron Dolan},
  journal={Behavioural pharmacology},
  year={2013},
  volume={24 4},
  pages={298-306}
}
Standardized Ginkgo biloba extract EGb 761 has been shown to inhibit inflammatory hyperalgesia in rats; however, the mechanism of action is not known. This study set out to investigate the anti-inflammatory and analgesic potential of bilobalide, a unique G. biloba constituent, in three well-characterized models of acute inflammatory pain. The effect of oral, intraplantar or intrathecal administration of bilobalide or drug-vehicle (0.25% agar; 10% ethanol in H2O) on responses to noxious thermal… CONTINUE READING

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