Biliverdin Reductase: More than a Namesake – The Reductase, Its Peptide Fragments, and Biliverdin Regulate Activity of the Three Classes of Protein Kinase C

Abstract

The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably unmatched by any single protein. hBVR is a Ser/Thr/Tyr-kinase, a scaffold protein, a transcription factor, and an intracellular transporter of gene regulators. hBVR is an upstream activator of the insulin/IGF-1 signaling pathway and of protein kinase C (PKC) kinases in the… (More)
DOI: 10.3389/fphar.2012.00031

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Cite this paper

@inproceedings{Gibbs2012BiliverdinRM, title={Biliverdin Reductase: More than a Namesake – The Reductase, Its Peptide Fragments, and Biliverdin Regulate Activity of the Three Classes of Protein Kinase C}, author={Peter E. M. Gibbs and Cicerone Tudor and Mahin. D. Maines}, booktitle={Front. Pharmacol.}, year={2012} }