Bilirubin mono- and di-glucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronyltransferase.

@article{Burchell1984BilirubinMA,
  title={Bilirubin mono- and di-glucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronyltransferase.},
  author={Brian Burchell and Norbert J. C. Blanckaert},
  journal={The Biochemical journal},
  year={1984},
  volume={223 2},
  pages={461-5}
}
Highly purified bilirubin UDP-glucuronyltransferase from Wistar-rat liver, when reconstituted with Gunn-rat liver microsomes (microsomal fraction), was able to catalyse the conversion of unesterified bilirubin into both bilirubin monoglucuronide and diglucuronide. Under zero-order kinetic conditions for monoglucuronide formation, the fraction of bilirubin… CONTINUE READING