Biliary tract: Newly identified biliatresone causes biliary atresia

  title={Biliary tract: Newly identified biliatresone causes biliary atresia},
  author={G. Patman},
  journal={Nature Reviews Gastroenterology &Hepatology},
  • G. Patman
  • Published 2015
  • Medicine
  • Nature Reviews Gastroenterology &Hepatology
  • Research from Michael Pack and Rebecca Wells’ groups published in Science Translational Medicine, has shed new light onto the aetiology of biliary atresia. Isolation of a previously unidentified isoflavonoid, biliatresone, from Dysphania plants has been found to cause damage to the extrahepatic biliary system in zebrafish larvae. These larvae develop a phenotype similar to that of human biliary atresia. Biliary atresia, a progressive disease of extrahepatic bile ducts (EHBD), although rare, is… CONTINUE READING