Biliary atresia: current concepts and research directions. Summary of a symposium.

  title={Biliary atresia: current concepts and research directions. Summary of a symposium.},
  author={William F. Balistreri and Richard D Grand and Jay H. Hoofnagle and Frederick J. Suchy and Frederick C. Ryckman and David H. Perlmutter and Ronald J. Sokol},
  volume={23 6},
Biliary atresia (BA) is the end result of a destructive, inflammatory process that affects intra- and extrahepatic bile ducts, leading to fibrosis and obliteration of the biliary tract with the development of biliary cirrhosis. It is the commonest cause of chronic cholestasis in infants and children, and therefore is the most frequent indication for liver transplantation in this age group. The disease occurs worldwide, affecting an estimated 1 in 8,000 to 12,000 live births. At present, there… CONTINUE READING
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