Biliary Tract Infections

@article{Westphal2012BiliaryTI,
  title={Biliary Tract Infections},
  author={J. F. Westphal and Jean Marie Brogard},
  journal={Drugs},
  year={2012},
  volume={57},
  pages={81-91}
}
Initial therapy of acute cholecystitis and cholangitis is directed towards general support of the patient, including fluid and electrolyte replacement, correction of metabolic imbalances and antibacterial therapy.Factors affecting the efficacy of antibacterial therapy include the activity of the agent against the common biliary tract pathogens and pharmacokinetic properties such as tissue distribution and the ratio of concentration in both bile and serum to the minimum inhibitory concentration… 

Antibiotics in the Biliary Tract: A Review of the Pharmacokinetics and Clinical Outcomes of Antibiotics Penetrating the Bile and Gallbladder Wall

  • A. Thabit
  • Medicine, Biology
    Pharmacotherapy
  • 2020
TLDR
Overall, most antibiotic classes exhibit biliary penetration that translates into clinical efficacy, but three antibiotics had positive clinical outcomes despite the lack of pharmacokinetic studies on their penetration into the biliary tract.

Acute Cholecystitis Caused by Vancomycin-Resistant Enterococcus faecium in a Morbidly Obese Patient with Multiple Co-Morbidities

TLDR
The first case of Vancomycin-resistant Enterococcus faecium acute cholecystitis in North America is reported, with a morbidly obese male with multiple comorbidities treated with antibiotics and ultrasound-guided percutaneous choleCystostomy tube placement.

[Acute cholangitis].

Infections of the biliary tract.

Antimicrobial management of intra-abdominal infections: literature's guidelines.

TLDR
The World Society of Emergency Surgery guidelines represent the conclusions of the consensus conference held in Bologna, Italy, in July 2010 during the first congress of the WSES.

Recurrent Pyogenic Cholangitis

Recurrent pyogenic cholangitis (RPC) is an inflammatory condition of the liver and biliary tree characterized by recurrent attacks of cholangitis associated with dilation and stricturing of the

Antibiotic Use in the Intensive Care Unit: Optimization and De-Escalation

TLDR
Based upon the most recent evidence, ICUs would benefit from employing empiric guidelines for antibiotic use, collecting appropriate specimens and implementing molecular diagnostics, optimizing the dosing of antibiotics, and reducing the duration of total therapy.

Role of Interventional Radiology in the Management of Acute Cholangitis.

TLDR
The role of biliary drainage performed by interventional radiology to manage acute cholangitis will be the focus, with specific scenarios where percutaneous drainage should be preferred over endoscopic drainage.

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TLDR
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