Biliary Innate Immunity: Function and Modulation

@inproceedings{Harada2010BiliaryII,
  title={Biliary Innate Immunity: Function and Modulation},
  author={Kenichi Harada and Yasuni Nakanuma},
  booktitle={Mediators of inflammation},
  year={2010}
}
Biliary innate immunity is involved in the pathogenesis of cholangiopathies in patients with primary biliary cirrhosis (PBC) and biliary atresia. Biliary epithelial cells possess an innate immune system consisting of the Toll-like receptor (TLR) family and recognize pathogen-associated molecular patterns (PAMPs). Tolerance to bacterial PAMPs such as lipopolysaccharides is also important to maintain homeostasis in the biliary tree, but tolerance to double-stranded RNA (dsRNA) is not found. In… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 68 references

CX 3 CL 1 ( fractalkine ) : a signpost for biliary inflammation in primary biliary cirrho

  • K. Harada S. Shimoda, H. Niiro
  • Hepatology
  • 2010

Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis

  • R. Dı́az, J. W. Kim, J.-J. Hui
  • Human Pathology, vol. 39, no. 1, pp. 102–115…
  • 2008
1 Excerpt

Similar Papers

Loading similar papers…