Bile salt-stimulated lipase and digestion of non-breast milk fat.

  title={Bile salt-stimulated lipase and digestion of non-breast milk fat.},
  author={P McClean and Marilyn Harding and W. Andrew Coward and Andrew M. Prentice and Steven Austin and Lawrence T. Weaver},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={26 1},
BACKGROUND 13 Carbon (13C)-lipid breath tests are an effective, noninvasive way of repeatedly measuring fat digestion. The purpose of this study was to assess the contribution of bile salt-stimulated lipase (BSSL) in human milk to the digestion of non-breast-milk fat in Gambian infants. METHODS Twelve Gambian infants (aged 3-8 months) were studied on 4 days. 13C-Trioctanoin (7.5 mg/kg, digested by BSSL preduodenal and pancreatic lipases) and 13C-cholesteryl octanoate (25 mg/kg, digested by… Expand
Mechanisms involved in malabsorption of dietary lipids
The C-MTG breath test correlates significantly with the extent of fat malabsorption in a rat model of impaired intestinal lipolysis, but the considerable interindividual variation of the C-Mixed triglyceride breath test does not support its application for diagnostic purposes in individual patients. Expand
Gastric and Postgastric Processing of 13C Markers Renders the 13C Breath Test an Inappropriate Measurement Method for the Gastric Emptying of Lipid Emulsions in Healthy Adults.
The chemical properties of the 13C marker and their gastric and postgastric interaction with fat renders 13CO2 excretion an inappropriate measure of LE emptying in healthy adults. Expand
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This review aims to place into perspective the traditional pancreatic exocrine function tests and the newer 13C breath tests. Expand
Stable isotope breath tests.
To what degree stable isotope breath tests fulfill the pediatrician's and scientist's needs is discussed, which can be performed in the ward, clinic, laboratory, and home. Expand
Stearic acid Oleic acid Linoleic acid α−Linolenic acid
  • 1998


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