Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid.

@article{Minich1999BileDI,
  title={Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid.},
  author={Deanna M Minich and M Kalivianakis and Rick Havinga and Harry van Goor and Frans Stellaard and Roel J Vonk and Folkert Kuipers and Henkjan J. Verkade},
  journal={Biochimica et biophysica acta},
  year={1999},
  volume={1438 1},
  pages={111-9}
}
Decreased bile secretion into the intestine has been associated with low plasma concentrations of essential fatty acids (EFA) in humans. We studied the mechanism behind this relationship by determining the status and absorption of the major dietary EFA, linoleic acid (LA), in control and 1-week bile-diverted rats. The absorption of LA was quantified by a balance method and by measuring plasma concentrations of [13C]LA after its intraduodenal administration. Absolute and relative concentrations… CONTINUE READING