Bile canalicular abnormalities in the early phase of a mouse model of sclerosing cholangitis.

Abstract

BACKGROUND The bile canaliculus is the smallest and first biliary channel and is formed by two or three adjacent hepatocytes. Previous studies of chronic cholangiopathies such as primary sclerosing cholangitis have focused on the bile ductules. However, little is known about the pathological alterations in bile canaliculi in the early phase of… (More)
DOI: 10.1016/j.dld.2012.09.007

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