Bile acids as regulators of hepatic lipid and glucose metabolism.

@article{Trauner2010BileAA,
  title={Bile acids as regulators of hepatic lipid and glucose metabolism.},
  author={Michael H. Trauner and Thierry Claudel and Peter Fickert and Tarek M. Moustafa and Martin Otto Werner Wagner},
  journal={Digestive diseases},
  year={2010},
  volume={28 1},
  pages={
          220-4
        }
}
Besides their well-established roles in dietary lipid absorption and cholesterol homeostasis, bile acids (BA) also act as metabolically active signaling molecules. The flux of reabsorbed BA undergoing enterohepatic circulation, arriving in the liver with the co-absorbed nutrients (e.g. glucose, lipids), provides a signal that coordinates hepatic triglyceride (TG), glucose and energy homeostasis. As signaling molecules with systemic endocrine functions, BA can activate protein kinases A and C as… CONTINUE READING
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