Bile acids. LV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid

Abstract

Abbreviations and trivial names: chenodeoxycholate, 3a,7adihydroxy-5p-cholanate; TLC, thin-layer chromatography; PLC, preparative-layer chromatography; HPLC, high-pressure liquid chromatography; PMR, proton magnetic resonance spectroscopy; GLC, gas-liquid chromatography; MS, mass spectrometry. Address correspondence to William H. Elliott, E. A. Doisy Department of Biochemistry, St. Louis University School of Medicine, 1402 South Grand Blvd., St. Louis, M O 63104. Shaw, R., and W. H. Elliott, unpublished observations. This paper reports the unequivocal identification of these side-products by comparison with the synthetic materials, and methods to reduce or eliminate their formation, thus providing an improved procedure for the derivatization of samples of chenodeoxycholic acid.

Cite this paper

@inproceedings{Shaw2002BileAL, title={Bile acids. LV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid}, author={Roger Shaw and William H. Elliott}, year={2002} }