Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease

@inproceedings{Mouzaki2016BileAA,
  title={Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease},
  author={Marialena Mouzaki and Alice Yuxin Wang and Robert Hj Bandsma and Elena M Comelli and Bianca Maria Arendt and Ling Zhang and Scott K. Fung and Sandra Fischer and Ian G. McGilvray and Johane P Allard},
  booktitle={PloS one},
  year={2016}
}
BACKGROUND & AIMS Non-alcoholic fatty liver disease (NAFLD) is characterized by dysbiosis. The bidirectional effects between intestinal microbiota (IM) and bile acids (BA) suggest that dysbiosis may be accompanied by an altered bile acid (BA) homeostasis, which in turn can contribute to the metabolic dysregulation seen in NAFLD. This study sought to examine BA homeostasis in patients with NAFLD and to relate that with IM data. METHODS This was a prospective, cross-sectional study of adults… CONTINUE READING

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The bidirectional effects between intestinal microbiota ( IM ) and bile acids ( BA ) suggest that dysbiosis may be accompanied by an altered bile acid ( BA ) homeostasis , which in turn can contribute to the metabolic dysregulation seen in NAFLD .
This was a prospective , cross - sectional study of adults with biopsy - confirmed NAFLD ( non - alcoholic fatty liver : NAFL or non - alcoholic steatohepatitis : NASH ) and healthy controls ( HC ) .
Non - alcoholic fatty liver disease ( NAFLD ) is characterized by dysbiosis .
This was a prospective , cross - sectional study of adults with biopsy - confirmed NAFLD ( non - alcoholic fatty liver : NAFL or non - alcoholic steatohepatitis : NASH ) and healthy controls ( HC ) .
Non - alcoholic fatty liver disease ( NAFLD ) is characterized by dysbiosis .
This was a prospective , cross - sectional study of adults with biopsy - confirmed NAFLD ( non - alcoholic fatty liver : NAFL or non - alcoholic steatohepatitis : NASH ) and healthy controls ( HC ) .
This was a prospective , cross - sectional study of adults with biopsy - confirmed NAFLD ( non - alcoholic fatty liver : NAFL or non - alcoholic steatohepatitis : NASH ) and healthy controls ( HC ) .
This was a prospective , cross - sectional study of adults with biopsy - confirmed NAFLD ( non - alcoholic fatty liver : NAFL or non - alcoholic steatohepatitis : NASH ) and healthy controls ( HC ) .
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