Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.

@article{Legry2017BileAA,
  title={Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects.},
  author={Vanessa Legry and Sven M Francque and Joel T. Haas and An Verrijken and Sandrine Caron and Oscar Ch{\'a}vez-Talavera and Emmanuelle Vallez and Luisa Vonghia and Eveline L Dirinck and Ann Verhaegen and Mostafa Kouach and Sophie Lestavel and Philippe Lefebvre and L Van Gaal and Anne Tailleux and R{\'e}jane Paumelle and Bart Staels},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2017},
  volume={102 10},
  pages={3783-3794}
}
Context Bile acids (BAs) are signaling molecules controlling energy homeostasis that can be both toxic and protective for the liver. BA alterations have been reported in obesity, insulin resistance (IR), and nonalcoholic steatohepatitis (NASH). However, whether BA alterations contribute to NASH independently of the metabolic status is unclear. Objective To assess BA alterations associated with NASH independently of body mass index and IR. Design and Setting Patients visiting the obesity… CONTINUE READING
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